Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10513438 | Journal of Clinical Epidemiology | 2015 | 28 Pages |
Abstract
The proportions of change in statistical significance from covariate adjustment of strongly prognostic characteristics were the same for small and large trials with similar gains in statistical power. Covariate adjustment is equally recommendable in small and large trials.
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Authors
Douglas D. Thompson, Hester F. Lingsma, William N. Whiteley, Gordon D. Murray, Ewout W. Steyerberg,