Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10513634 | Journal of Clinical Epidemiology | 2015 | 11 Pages |
Abstract
Multiple SRs agreed in their qualitative conclusions but not on reporting and on analyses of hard outcomes. Discordance on significance of treatment effects was due to a combination of variation in design with inclusion of different studies and lack of precision for single hard outcomes compared with a composite outcome. Such inconsistencies among SRs could potentially slow the translation of SRs' results to clinical and public health decision making and suggest the need for a broader methodological and clinical agreement on their design.
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Authors
Ersilia Lucenteforte, Lorenzo Moja, Valentina Pecoraro, Andrea A. Conti, Antonio Conti, Elena Crudeli, Alessio Galli, Gian Franco Gensini, Martina Minnelli, Alessandro Mugelli, Riccardo Proietti, Jonida Shtylla, Roberto D'Amico, Elena Parmelli,