Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10513822 | Journal of Clinical Epidemiology | 2015 | 10 Pages |
Abstract
None of the end points in this study were found to achieve the level of evidence (ie, mean R2trial > 0.60) that has been set to select high or excellent correlation levels by common surrogate evaluation tools. Previous surrogacy relationships observed between PFS and TTP vs. OS in selected settings may not apply across other classes or lines of therapy.
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Authors
Oriana Ciani, Marc Buyse, Ruth Garside, Jaime Peters, Everardo D. Saad, Ken Stein, Rod S. Taylor,