Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10513964 | Journal of Clinical Epidemiology | 2012 | 8 Pages |
Abstract
In sum, these findings show that the adaptation method is useful when validating or applying a composite end point prediction model to the individual component outcomes. Following from this, recommendations concerning reporting of composite end points in future research are also included. Without the need for extra data, composite end point prediction models can easily be directly expanded to allow for the estimation of risk for each individual component outcome, improving the interpretability for clinicians and patients.
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Authors
Martijn J.A. Gondrie, Kristel J.M. Janssen, Karel G.M. Moons, Yolanda van der Graaf,