Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10514218 | Journal of Clinical Epidemiology | 2013 | 11 Pages |
Abstract
The unanticipated finding of a positive average true effect and superiority of the new treatment in most NI trials suggest that the current practice of choosing NI designs in clinical trials makes degradation on average unlikely. However, the distribution of true treatment effects demonstrates that, in some NI trials, the new treatment is distinctly inferior.
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Authors
Beryl Primrose Gladstone, Werner Vach,