Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10514261 | Journal of Clinical Epidemiology | 2012 | 8 Pages |
Abstract
Moderate gains in power may be obtained using covariate adjustment from logistic regression in heterogeneous conditions such as TBI. Although analyses of RCTs might consider covariate adjustment to improve power, we caution against this approach in the planning of RCTs.
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Authors
Elizabeth L. Turner, Pablo Perel, Tim Clayton, Phil Edwards, Adrian V. Hernández, Ian Roberts, Haleema Shakur, Ewout W. Steyerberg, CRASH trial collaborators CRASH trial collaborators,