Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10514378 | Journal of Clinical Epidemiology | 2009 | 8 Pages |
Abstract
The analysis of this new endpoint led to an odds ratio allowing detection of improvement and detriment. In the simulation study, this endpoint was associated with the largest statistical power by increasing the amount of information used as compared with usual endpoints. We recommend this new endpoint formulation in the formal development of a new vaccination regimen, whenever applicable.
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Authors
Gaëlle Pédrono, Rodolphe Thiébaut, Ahmadou Alioum, Philippe Lesprit, Bernard Fritzell, Yves Lévy, Geneviève Chêne,