Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10528644 | Analytica Chimica Acta | 2005 | 5 Pages |
Abstract
A flow system based on the multicommutation is proposed for fast and clean determination of cyclamate. The procedure exploits the reaction of cyclamate with nitrite in acidic medium and the spectrophotometric determination of the excess of nitrite by iodometry. The flow system was designed with a set of solenoid micro-pumps to minimize reagent consumption and waste generation. The detection limit was estimated as 30 μmol Lâ1 (99.7% confidence level) with linear response ranging up to 3.0 mmol Lâ1. The coefficient of variation was estimated as 1.7% for a solution containing 2.0 mmol Lâ1 cyclamate (n = 20). About 60 samples can be analyzed per hour, consuming only 3 mg KI and 1.3 μg NaNO2, and generating 2.0 mL of effluent per determination, thus providing an environmentally friendly alternative to previously proposed procedures. Common artificial and natural sweeteners did not interfere when present in concentrations 10-times higher than cyclamate. The procedure was successfully applied for determination of cyclamate in artificial table sweeteners with results in agreement with the reference method at the 95% confidence level.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Fábio R.P. Rocha, Eva Ródenas-Torralba, Ángel Morales-Rubio, Miguel de la Guardia,