Article ID Journal Published Year Pages File Type
10537106 Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 2013 11 Pages PDF
Abstract
► Elastic network of torsion angles representing all protein atoms ► Null-model of “random” conformation changes based on linear response theory ► Significant deviations suggest functional motions with small energy barriers. ► They occur more frequently for phosphorylation, dimeric proteins, ligand binding. ► Reconcile in a unique framework conformational selection and induced fit.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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