Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10537106 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2013 | 11 Pages |
Abstract
⺠Elastic network of torsion angles representing all protein atoms ⺠Null-model of “random” conformation changes based on linear response theory ⺠Significant deviations suggest functional motions with small energy barriers. ⺠They occur more frequently for phosphorylation, dimeric proteins, ligand binding. ⺠Reconcile in a unique framework conformational selection and induced fit.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Helena G. Dos Santos, Javier Klett, Raúl Méndez, Ugo Bastolla,