Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10736868 | Experimental Gerontology | 2013 | 6 Pages |
Abstract
⺠SIRT3 regulates the balance between ROS generation and ROS detoxification. ⺠SIRT3 binds and deacetylates enzymes that promote ROS clearance and maintain redox. ⺠SIRT3 loss creates an environment of increased oxidative stress.
Keywords
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Ageing
Authors
Alexandra S. Bause, Marcia C. Haigis,