Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10736930 | Experimental Gerontology | 2013 | 8 Pages |
Abstract
⺠DR delays the reduction in replicative lifespan associated with chronological age. ⺠MMP during chronological aging predicts subsequent replicative lifespan. ⺠Chronologically aged cells with highest MMP cannot complete a cell division. ⺠Chronologically aged cells with lowest MMP maintain a full replicative lifespan.
Keywords
Related Topics
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Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Joe R. Delaney, Christopher Murakami, Annie Chou, Daniel Carr, Jennifer Schleit, George L. Sutphin, Elroy H. An, Anthony S. Castanza, Marissa Fletcher, Sarani Goswami, Sean Higgins, Mollie Holmberg, Jessica Hui, Monika Jelic, Ki-Soo Jeong, Jin R. Kim,