| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10737031 | Experimental Gerontology | 2011 | 5 Pages |
Abstract
⺠Drosophila melanogaster contains tissues that are maintained by adult stem cells. ⺠Aging leads to a decline in number and activity of Drosophila germ line stem cells. ⺠Aging results in compromised niche function in the Drosophila germ line. ⺠Aging leads to increased proliferation of Drosophila intestinal stem cells (ISCs), which is accompanied by mis-differentiation of progenitors. ⺠Pathways that regulating longevity, such as the Insulin/IGF pathway, regulate stem cell behavior in Drosophila.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Lei Wang, D. Leanne Jones,