| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10737040 | Experimental Gerontology | 2011 | 7 Pages |
Abstract
⺠Multiple laboratories have studied Drosophila stocks with specific experimentally-evolved aging patterns aiming to estimate the number of genes involved in aging. ⺠Historically, these studies have tended to uncover a large number of putative genetic mechanisms in the control of aging. ⺠Recent genome-wide surveys suggest that hundreds of loci have undergone changes in allele frequency or gene expression as a result of selection for slowed aging. ⺠Understanding the functional consequences of all of these loci presents a significant challenge to the field of aging research.
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Authors
Michael R. Rose, Molly K. Burke,