Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10737047 | Experimental Gerontology | 2012 | 5 Pages |
Abstract
⺠CAA is an age-associated disease with amyloid deposition in brain vessel walls. ⺠CAA causes mechanical and non-mechanical complications. ⺠CAA non-mechanical cerebrovascular dysregulation are common and more deleterious than mechanical. ⺠Aβ 1-40 disrupt cerebrovascular regulation via endothelial-dependent factors. ⺠The non-mechanical changes may explain cognitive decline in CAA.
Keywords
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Authors
Lea Tenenholz Grinberg, Amos D. Korczyn, Helmut Heinsen,