Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10737052 | Experimental Gerontology | 2012 | 5 Pages |
Abstract
⺠We review the genetics of MRI correlates of subcortical vascular dementia (sVaD). ⺠MRI correlates of sVaD includes white matter lesions, lacunes and microbleeds. ⺠White matter lesions are highly heritable. ⺠SNPs in APOE, NOTCH3 and the renin-angiotensin system are associated with sVaD. ⺠The first gemone wide association study identifies novel genes on chromosome 17.
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Authors
Helena Schmidt, Paul Freudenberger, Stephan Seiler, Reinhold Schmidt,