| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10737062 | Experimental Gerontology | 2011 | 8 Pages |
Abstract
⺠Immunosenescence-related transcripts profiled in PBMC of elderly with hip fracture. ⺠29 differentially abundant transcripts identified in acute phase vs healthy ageing. ⺠7 of these transcripts differentially abundant in PBMC of aged vs young controls. ⺠CD28, CD69, LCK, CTSD, HMOX1, TNFRSF1A further altered after hip fracture. ⺠Comparison to geriatric infections includes commonalities with hip fracture.
Keywords
PBMCIGF-1IL-10ADLRT-qPCRTCrMMSEIL-6IADLIFN-γCIRS-GPMTcDNAcomplementary deoxyribonucleic acidinflammationinsulin-like growth factor-1Immunosenescenceinterferon-γInterleukin-10interleukin-6Mini-Mental Status ExaminationGene expressionEnzyme-linked immunosorbent assayELISAOxidative stresstumor necrosis factor-alphaVersusAgeingperipheral blood mononuclear cellsbody mass indexBMIHip fractureTNF-αPhotomultiplierActivities of daily livingC-reactive proteinCRPT cell receptor
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Thi Kim Duy Vo, Patrice Godard, Marie de Saint-Hubert, Gabriel Morrhaye, Florence Debacq-Chainiaux, Christian Swine, Vincent Geenen, Henri J. Martens, Olivier Toussaint,