Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10748833 | Biochemical and Biophysical Research Communications | 2016 | 17 Pages |
Abstract
HOTAIR upregulation in cardiomyocytes of LPS-induced sepsis mice promoted TNF-α production in the circulation by activating NF-κB, involving the phosphorylation of NF-κB p65 subunit. Moreover, HOTAIR silence preserved cardiac function of sepsis mice during LPS-induced sepsis.
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Authors
Hongwei Wu, Jinfeng Liu, Wei Li, Gang Liu, Zhenguang Li,