Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10749262 | Biochemical and Biophysical Research Communications | 2015 | 6 Pages |
Abstract
GLP1-mimetic/DPP-4 inhibitor act either directly (through GLP-1R) or indirectly (by restoring DPP-4-induced signaling impairment) to activate Ras/MAPK/ERK signaling which stimulate LXR-α to upregulate ABCA1/ABCG1 ultimately increasing cholesterol efflux.
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Authors
Ahmed M. Mostafa, Nadia M. Hamdy, Hala O. El-Mesallamy, Sherif Z. Abdel-Rahman,