Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10749409 | Biochemical and Biophysical Research Communications | 2015 | 6 Pages |
Abstract
In this study, we revealed, for the first time, that ZSCAN4 indirectly interacts with TRF1 (functional association protein) in cancer cells. Furthermore, we show that ZSCAN4 plays an important role independent of telomere maintenance pathways (telomerase positive and ALT) or cell lineage.
Keywords
PinX1Zscan4telomeric repeat binding factor 1GSTTRF1BiFCtelomeric repeat binding factor 2ALTTRF2RAP1POT1TPP1TIN2tripeptidyl peptidase 1TelomeraseTelomeresbimolecular fluorescence complementationprotection of telomeres 1ESCCancerEmbryonic stem cellsCo-IPAlternative lengthening of telomeresCo-Immunoprecipitationglutathione S-transferase
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Kyungwoo Lee, Lauren S. Gollahon,