Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10750426 | Biochemical and Biophysical Research Communications | 2015 | 6 Pages |
Abstract
Tamoxifen may induce changes in body composition, whole body glucose and lipid metabolism and has significant effects on AT biology, which need to be considered when using Tamoxifen as a tool to induce conditional transgenic mouse models. Our data further suggest that tamoxifen-treated wildtype mice should be characterized in parallel to experimental transgenic models to control for tamoxifen administration effects.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Nico Hesselbarth, Chiara Pettinelli, Martin Gericke, Claudia Berger, Anne Kunath, Michael Stumvoll, Matthias Blüher, Nora Klöting,