Article ID Journal Published Year Pages File Type
10751808 Biochemical and Biophysical Research Communications 2015 8 Pages PDF
Abstract
Our findings suggest that TDP-43 and FUS controls Drosha stability in Neuro 2A cells and that a phosphomimetic mutant TDP-43 (S409/410E) which is associated with Drosha instability can induce neuronal toxicity.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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A phosphomimetic mutant TDP-43 (S409/410E) induces Drosha instability and cytotoxicity in Neuro 2A cells
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