Article ID Journal Published Year Pages File Type
10752471 Biochemical and Biophysical Research Communications 2015 8 Pages PDF
Abstract
Ghrelin prevented the breakdown of intestinal barrier function in DSS-induced colitis. The protective effects of ghrelin on intestinal barrier function were mediated by its receptor GHSR-1a. The inhibition of NF-κB activation might be part of the mechanism underlying the effects of ghrelin that protect against barrier dysfunction.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Ghrelin ameliorates intestinal barrier dysfunction in experimental colitis by inhibiting the activation of nuclear factor-kappa B
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