| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10755109 | Biochemical and Biophysical Research Communications | 2014 | 6 Pages |
Abstract
High phosphorus induced calcification of mature adipocytes, and adipocytes exposed to elevated phosphorus can induce calcification of VSMC in a paracrine manner. Sodium thiosulfate inhibited this calcification and decreased the secretin of leptin and VEGF from adipocytes. These results suggest that adipocyte exposure to elevated phosphorus may be a pathogenic factor in calcification observed in the skin in calciphylaxis and other diseases.
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Authors
Neal X. Chen, Kalisha O'Neill, Nader Kassis Akl, Sharon M. Moe,