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Losartan inhibits endothelial-to-mesenchymal transformation in mitral valve endothelial cells by blocking transforming growth factor-β-induced phosphorylation of ERK

Article ID Journal Published Year Pages File Type
10755572 Biochemical and Biophysical Research Communications 2014 6 Pages PDF
Keywords
α-SMAEndMTTGFβERKVECEBMAT1AT2SMADangiotensin II type 1 receptorAngiotensin IIα-smooth muscle actintransforming growth factor-βmitral valveAng IIEndothelial cellslosartanendothelial basal mediumAngiotensin II type 2 receptor
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Losartan inhibits endothelial-to-mesenchymal transformation in mitral valve endothelial cells by blocking transforming growth factor-β-induced phosphorylation of ERK
Authors
Jill Wylie-Sears, Robert A. Levine, Joyce Bischoff,
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Journal
Biochemical and Biophysical Research Communications
Journal: Biochemical and Biophysical Research Communications
Related Categories
α-SMA
EndMT
TGFβ
ERK
VEC
EBM
AT1
AT2
SMAD
angiotensin II type 1 receptor
Angiotensin II
α-smooth muscle actin
transforming growth factor-β
mitral valve
Ang II
Endothelial cells
losartan
endothelial basal medium
Angiotensin II type 2 receptor
Ageing
Biochemistry
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Biotechnology
Cancer Research
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Clinical Biochemistry
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