Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10755649 | Biochemical and Biophysical Research Communications | 2014 | 6 Pages |
Abstract
We therefore hypothesise: (a) sclerostin exists in multiple forms not associated with the mineralised state of the cell/tissue and (b) circulating sclerostin is dimeric, as is the sclerostin found in non-musculoskeletal soft tissues. These observations may have significant implications for the therapeutic modulation of sclerostin.
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Authors
Paula Hernandez, Ciara Whitty, R. John Wardale, Frances M.D. Henson,