Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10755762 | Biochemical and Biophysical Research Communications | 2014 | 15 Pages |
Abstract
- Two novel introns are inserted in AGT from selected ray-finned fishes.
- AGT is conserved on same syntenic fragment from 500 MY.
- AGT became non-inhibitory from inhibitory serpin via RCL mutations.
- AGT has 690 variants in 1092 human genomes from 14 populations.
- 121 missense variants identified in human AGT protein with 32 deleterious mutants.
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Authors
Abhishek Kumar, Sandeep J. Sarde, Anita Bhandari,