Article ID Journal Published Year Pages File Type
10755762 Biochemical and Biophysical Research Communications 2014 15 Pages PDF
Abstract

- Two novel introns are inserted in AGT from selected ray-finned fishes.
- AGT is conserved on same syntenic fragment from 500 MY.
- AGT became non-inhibitory from inhibitory serpin via RCL mutations.
- AGT has 690 variants in 1092 human genomes from 14 populations.
- 121 missense variants identified in human AGT protein with 32 deleterious mutants.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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