| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10755839 | Biochemical and Biophysical Research Communications | 2014 | 7 Pages |
Abstract
We could detect six different classes of highly potent inhibitors of PrPSc propagation in vitro and identified piperazine derivatives as a new inhibitory lead structure, which increased incubation time of scrapie infected mice.
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Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Fabienne Leidel, Martin Eiden, Markus Geissen, Thomas Hirschberger, Paul Tavan, Armin Giese, Hans A. Kretzschmar, Hermann Schätzl, Martin H. Groschup,