| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10756067 | Biochemical and Biophysical Research Communications | 2014 | 6 Pages |
Abstract
1,2,3,4,6-Penta-O-galloyl-β-d-glucose(PGG) specifically target fatty acid synthase for cancer therapy by being transported across cancer cell membranes, inhibiting FAS expression and activating caspase in cancer cells by competition with Mal-CoA or NADPH without inducing conformational changes or the precipitation of FAS.
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Authors
Wenhua Zhao, Yuji Wang, Weijia Hao, Ming Zhao, Shiqi Peng,