Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10756289 | Biochemical and Biophysical Research Communications | 2014 | 6 Pages |
Abstract
- CD44 variant8-10 and c-Myc are inversely expressed in gastric cancer cells.
- Redox-stress enhances c-Myc expression via canonical Wnt signal.
- CD44v, but not CD44 standard, suppresses redox stress-induced Wnt activation.
- CD44v expression promotes both transcription and proteasome degradation of c-Myc.
- Inversed expression pattern between CD44v and c-Myc is often recognized in vivo.
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Authors
Go J. Yoshida, Hideyuki Saya,