Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10756991 | Biochemical and Biophysical Research Communications | 2013 | 7 Pages |
Abstract
- Sirt2 expression is down-regulated in human glioma tissues and cell lines.
- Sirt2 regresses glioma cell growth and colony formation via inducing apoptosis.
- miR-21 is essential for the functions of Sirt2 in glioma cells.
- Sirt2 deacetylates p65 to decrease miR-21 expression.
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Authors
Ya'nan Li, Dongwei Dai, Qiong Lu, Mingyu Fei, Mengmeng Li, Xi Wu,