Article ID Journal Published Year Pages File Type
10756991 Biochemical and Biophysical Research Communications 2013 7 Pages PDF
Abstract

- Sirt2 expression is down-regulated in human glioma tissues and cell lines.
- Sirt2 regresses glioma cell growth and colony formation via inducing apoptosis.
- miR-21 is essential for the functions of Sirt2 in glioma cells.
- Sirt2 deacetylates p65 to decrease miR-21 expression.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , , , , ,