| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10757203 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
- First report on the role of AQP5 in maintaining lens transparency and homeostasis.
- AQP5 regulates lens osmotic balance.
- AQP5 knockout lens exhibits osmotic swelling and develops hyperglycemic cataract.
- Glucose transporters and cotransporters cause hyperglycemia-induced water influx.
- AQP5 is critical for protecting the lens from diabetic and senile cataracts.
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Authors
S. Sindhu Kumari, Kulandaiappan Varadaraj,