| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10757287 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
- In the rat brain deep cortex, injury induced spreading of neuronal death.
- Injury also induced astrocyte activation with connexin 43 (Cx43) up-regulation.
- Injury induced opening of astrocytic Cx43-hemichannel (HC) and neuronal Cx36-HC.
- The opening of the HCs induces the spread of neuronal death through μ-calpain activation.
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Authors
Yasuhiro Ishii, Kaori Shintani-Ishida, Ken-ichi Yoshida,