Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10757472 | Biochemical and Biophysical Research Communications | 2014 | 7 Pages |
Abstract
- EpCAM is heterogeneously expressed in prostate cancer both in vitro and in vivo.
- mTOR signaling is differentially regulated in EpCAM-high and -low subpopulations.
- EpCAM induces the susceptibility to EGF ligand and sustained EGFR activation.
- There is a positive correlation between EpCAM and LAT1 expression.
- EpCAM works as a sensor for the available growth factors to activate AMPK signal.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Go J. Yoshida, Hideyuki Saya,