Article ID Journal Published Year Pages File Type
10757784 Biochemical and Biophysical Research Communications 2013 5 Pages PDF
Abstract

- The structure of PA2196: dsDNA complex revealed that two dimers bind to one dsDNA.
- This binding mode is similar to that of QacR in that two dimers bind to one dsDNA.
- Residues in the α3 helix mainly interact with the base and phosphate of dsDNA.
- PA2196 undergoes large conformational changes upon DNA binding.
- The structure of PA2196: dsDNA complex help understand the recognition mechanism.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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