Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10758035 | Biochemical and Biophysical Research Communications | 2013 | 7 Pages |
Abstract
- We constructed polycistronic plasmid carrying four reprogramming factor (OSKM).
- Human adipose mesenchymal stem cells were reprogrammed into iPS cells.
- ADSCs derived iPS cells switch to neural differentiation after induction.
- Neural differentiated cells had normal karyotypes and no insertion mutation.
- The method provides potential strategy for patient-specific neural cells therapy.
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Authors
Xinjian Qu, Tianqing Liu, Kedong Song, Xiangqin Li, Dan Ge,