Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10758068 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
- Kamolonol inhibits Ang II-induced stress fiber formation in H9c2 cells.
- Kamolonol suppresses Ang II-induced cellular hypertrophy in H9c2 cells.
- Kamolonol possesses a potent ROCK2 inhibitory activity.
- Kamolonol decreases Ang II-induced phosphorylation of MYPT and MLC.
- Anti-fibrotic and anti-hypertrophic effects may be due to blocking ROCK2 pathway.
Keywords
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Authors
Mun Sun Kim, Kwang-Seok Oh, Jeong Hyun Lee, Shi Yong Ryu, Jihye Mun, Byung Ho Lee,