Article ID Journal Published Year Pages File Type
10758068 Biochemical and Biophysical Research Communications 2013 6 Pages PDF
Abstract

- Kamolonol inhibits Ang II-induced stress fiber formation in H9c2 cells.
- Kamolonol suppresses Ang II-induced cellular hypertrophy in H9c2 cells.
- Kamolonol possesses a potent ROCK2 inhibitory activity.
- Kamolonol decreases Ang II-induced phosphorylation of MYPT and MLC.
- Anti-fibrotic and anti-hypertrophic effects may be due to blocking ROCK2 pathway.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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