Article ID Journal Published Year Pages File Type
10758223 Biochemical and Biophysical Research Communications 2013 6 Pages PDF
Abstract

- ATP killed astrocytes, but inhibited their P2X7R basal activity.
- Non-stimulated astrocytes incorporated beads into the intracellular space.
- Cytocharasine D, and P2X7R agonists and antagonists inhibited the bead uptake.
- Down-regulation of astrocytic P2X7R decreased the bead uptake.
- Collectively, P2X7Rs in resting astrocytes regulates their engulfing activity.
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