Article ID Journal Published Year Pages File Type
10758408 Biochemical and Biophysical Research Communications 2013 6 Pages PDF
Abstract

- Mitochondria dysfunction and oxidative stress are thought to cause insulin resistance.
- High fat feeding causes glucose intolerance in mice and promotes lipid oxidation in tissues.
- Increased Sod1 or Sod2 prevented obesity-induced glucose intolerance and lipid oxidation.
- No change in mitochondrial function in muscle from high fat fed mice.
- Increased Sod1, but not Sod2, reduced mitochondrial ROS and increased ATP production.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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