| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10758488 | Biochemical and Biophysical Research Communications | 2013 | 7 Pages |
Abstract
- First report on the platelet toxic action of melatonin.
- Melatonin induces apoptosis by generation of ROS.
- Melatonin augments intracellular Ca2+ and damage mitochondria.
- Melatonin induces release of Cyt c and activate caspases and kinases.
- Finally, melatonin induces phosphatidyl serine exposure leading to apoptosis.
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Authors
Kesturu Subbaiah Girish, Manoj Paul, Ram Mohan Thushara, Mahadevappa Hemshekhar, Mahalingam Shanmuga Sundaram, Kanchugarakoppal Subbegowda Rangappa, Kempaiah Kemparaju,