Article ID Journal Published Year Pages File Type
10758488 Biochemical and Biophysical Research Communications 2013 7 Pages PDF
Abstract

- First report on the platelet toxic action of melatonin.
- Melatonin induces apoptosis by generation of ROS.
- Melatonin augments intracellular Ca2+ and damage mitochondria.
- Melatonin induces release of Cyt c and activate caspases and kinases.
- Finally, melatonin induces phosphatidyl serine exposure leading to apoptosis.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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