| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10758530 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
- FAK signaling cascade in cancer cells is profoundly inhibited by methyl violet 2B.
- Methyl violet 2B identified by virtual screening is a novel allosteric FAK inhibitor.
- Methyl violet 2B possesses extremely high kinase selectivity.
- Methyl violet 2B suppresses strongly the proliferation of cancer cells.
- Methyl violet 2B inhibits focal adhesion, invasion and migration of cancer cells.
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Authors
Hwan Kim, Nam Doo Kim, Jiyeon Lee, Gyoonhee Han, Taebo Sim,