| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10758849 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠MPA and NET-A have similar binding affinities for hMR but 100-fold lower than Prog. ⺠Unlike Prog, MPA and NET-A have weak MR antagonistic activity on a reporter gene. ⺠Unlike MPA, NET-A has similar antagonistic activity as Prog on endogenous genes. ⺠NET-A, not MPA, dissociates between transrepression and transactivation via the hMR. ⺠Results suggest NET-A and MPA may result in differential side-effects via the MR.
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Authors
Donita Africander, Renate Louw, Janet P. Hapgood,