| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10758870 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
- We developed a new 3D multicellular heterospheroid tumor model in hydrogel system.
- It incorporates three aspects of cancer: 3D, multicellularity, and ECM barrier.
- The 3D heterospheroid model is more resistant to drug over 2D monolayer culture.
- Stromal fibroblasts and collagen gel provide more resistance to anti-cancer drug.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Derek Yip, Cheul H. Cho,