Article ID Journal Published Year Pages File Type
10759181 Biochemical and Biophysical Research Communications 2013 7 Pages PDF
Abstract

- miR-19a/b was upregulated in multidrug-resistant gastric cancer cell lines.
- Overexpression of miR-19a/b decreased sensitivity to anticancer drugs.
- miR-19a/b accelerated the efflux of chemotherapeutics.
- miR-19a/b inhibited drug induced apoptosis. PTEN is a functional target of miR-19a/b in MDR of gastric cancer.
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