Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10759181 | Biochemical and Biophysical Research Communications | 2013 | 7 Pages |
Abstract
- miR-19a/b was upregulated in multidrug-resistant gastric cancer cell lines.
- Overexpression of miR-19a/b decreased sensitivity to anticancer drugs.
- miR-19a/b accelerated the efflux of chemotherapeutics.
- miR-19a/b inhibited drug induced apoptosis. PTEN is a functional target of miR-19a/b in MDR of gastric cancer.
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Authors
Fang Wang, Ting Li, Bin Zhang, Hong Li, Qiong Wu, Li Yang, Yongzhan Nie, Kaichun Wu, Yongquan Shi, Daiming Fan,