| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10759590 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
- Anticancer effects of B4, a novel berberine-bile acid analog, were tested.
- B4 inhibited cell proliferation in hepatocellular carcinoma cells.
- It also stimulated mitochondrial ROS production and membrane depolarization.
- Effects of B4 were inhibited by a non-specific ROS scavenger.
- Regulation of ROS generation may be a strategy for treating hepatic carcinoma.
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Authors
Qingyong Li, Li Zhang, Yuangang Zu, Tianyu Liu, Baoyou Zhang, Wuna He,