Article ID Journal Published Year Pages File Type
10759644 Biochemical and Biophysical Research Communications 2013 6 Pages PDF
Abstract

- Phenylaminonaphthoquinones are redox cyclers able to form ROS.
- Phenylaminonaphthoquinones plus ascorbate inhibit T24 cell growth.
- Phenylaminonaphthoquinones plus ascorbate lead to necrotic-like cell death.
- Phenylaminonaphthoquinones plus ascorbate impair cell cycle and affect MAPKs.
- Phenylaminonaphthoquinones plus ascorbate induce a senescent cancer cell phenotype.
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