Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10759644 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
- Phenylaminonaphthoquinones are redox cyclers able to form ROS.
- Phenylaminonaphthoquinones plus ascorbate inhibit T24 cell growth.
- Phenylaminonaphthoquinones plus ascorbate lead to necrotic-like cell death.
- Phenylaminonaphthoquinones plus ascorbate impair cell cycle and affect MAPKs.
- Phenylaminonaphthoquinones plus ascorbate induce a senescent cancer cell phenotype.
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Authors
K.B. Felipe, J. Benites, C. Glorieux, B. Sid, M. Valenzuela, M.R. Kviecinski, R.C. Pedrosa, J.A. Valderrama, Ph. Levêque, B. Gallez, J. Verrax, P. Buc Calderon,