| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10759670 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠IDH1/2 mutations are early and frequent genetic alterations in gliomas. ⺠We established anti-mutated IDH2-specific mAbs KMab-1 and MMab-1. ⺠KMab-1 or MMab-1 specifically reacted with mutated IDH2 in ELISA. ⺠MMab-1 specifically stained IDH2-R172M-expressing CHO cells in ICC. ⺠MMab-1 specifically stained IDH2-R172M-expressing gliomas in IHC.
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Authors
Mika Kato Kaneko, Shunpei Morita, Yuta Tsujimoto, Ryo Yanagiya, Kana Nasu, Hiroko Sasaki, Yasukazu Hozumi, Kaoru Goto, Atsushi Natsume, Mika Watanabe, Toshihiro Kumabe, Shingo Takano, Yukinari Kato,