| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10759711 | Biochemical and Biophysical Research Communications | 2013 | 7 Pages |
Abstract
⺠Atoh1 plays crucial roles in the differentiation of colon. ⺠Stabilized Atoh1 protein directly induces Lgr5 in colon cancer. ⺠Atoh1 enriches colon cancer stem cells. ⺠Atoh1 acquires both malignant potential and mucinous phenotype. ⺠Atoh1 mimics mucinous colon cancer.
Keywords
Tcf4SRCCATOH1TFF3leucine-rich repeat-containing G-protein coupled receptor 5Muc2LGR5RLUGSK3RT-PCRSignet ring cell carcinomaIntestinal epithelial cellscancer stem cellTrefoil factor 3Mucin 2atonal homolog 1relative light unitsreverse-transcription polymerase chain reactionChemoresistanceIECglycogen synthase kinase 3
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Yoshihito Kano, Kiichiro Tsuchiya, Xiu Zheng, Nobukatsu Horita, Keita Fukushima, Shuji Hibiya, Yuhki Yamauchi, Tatsunori Nishimura, Kunihiko Hinohara, Noriko Gotoh, Shinji Suzuki, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe,