| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10759737 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠HDAC inhibitors decrease the stability of ERα mRNA in MCF-7 cells. ⺠HDAC3 is involved in maintaining ERα mRNA stability in MCF-7 cells. ⺠ERα mRNA instability by knockdown of HDAC3 reduces the estrogen-dependent proliferation of ERα-positive MCF-7 cells. ⺠HDAC3 specific inhibitor will be one of new drugs for ERα-positive breast cancers.
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Authors
Shohei Oie, Kazuya Matsuzaki, Wataru Yokoyama, Akiko Murayama, Junn Yanagisawa,