Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10759742 | Biochemical and Biophysical Research Communications | 2013 | 7 Pages |
Abstract
⺠PRIP is a novel negative modulator in nutrient depletion-induced autophagy. ⺠PRIP, a binding partner of GABARAP, interacts with an autophagy initiator, LC3. ⺠Enhanced PRIP colocalization with LC3 occurs in starved MEFs. ⺠PRIP deficiency increases autophagosome formation in starved MEFs. ⺠PRIP overexpression inhibits autophagosome formation in starved MEFs.
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Authors
Hisanori Umebayashi, Akiko Mizokami, Miho Matsuda, Kae Harada, Hiroshi Takeuchi, Isei Tanida, Masato Hirata, Takashi Kanematsu,