| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10759749 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠PODXL enhances adhesion/migration of CHO cells and activates of Rac1/Cdc42 GTPases. ⺠Activation of small GTPases parallels the effects of PODXL deletion mutants. ⺠Suppression of rac1 abolishes the effects of PODXL. ⺠Extracellular and DTHL domains are required for enhancing adhesion but not migration. ⺠Integrity of the cytosolic domain is essential for enhancing adhesion and migration.
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Authors
DarÃo Fernández, Angélica Horrillo, Carolina Alquezar, Consuelo González-Manchón, Roberto Parrilla, Matilde S. Ayuso,